Jang, Hye-Ock  사진
Jang, Hye-Ock
POSITION
Professor/Korean Medicine Doctor/Ph.D.
CONTACT
jho9612@pusan.ac.kr, +82-51-510-8236
SPHERE
Korean Medicine/Dental pharmacology
OFFICE
Department of dental pharmacology

Education

1995. 03 - 1997. 02  MD, College of Oriental Medicine, Dong-Eui University, Pusan, Korea
1999. 03 - 2002. 02  KMD, College of Oriental Medicine, Dong-Eui University, Pusan, Korea
2003. 03 - 2005. 02  Ph.D., School of  Dentistry, Pusna National University, Pusan, Korea 


Professional experience

1995. 03 - 1999. 08  Assistant
                            College of Oriental Medicine, Dongeui University
1999. 09 - 2004. 02  Full-time researcher
                            Research Institute for Oral Biotechnology, Pusan National University
2004. 03 - 2008. 02  Assistant Professor
                            College of Dentistry, Pusan National University 

2008. 03 - 2013. 02  Associate Professor
                            School of Dentistry, Pusan National University
2013. 03 -               Professor
                            School of Dentistry, Pusan National University
2005. 08 -               Director, Research Institute for Oral Biotechnology, Pusan National University

 

Research Interests

1.  Proteins-lipids interactions
2.  Molecular mechanisms of Anti-inflammatory and anti-cancer using natural extracts 


Main article

1. CS Park, SM Lee, IK Chung, JB Kim, WS Son, HO Jang and I Yun, The Distribution of Barbiturates in Model Membranes of Total Lipids and Total Phospholipids Extracted from Brain Membranes, Journal of Biochemistry and Molecular Biology, 33(3):221-227, 2000 (SCIE)

2. IK Chung, DG Kim, YZ Chung, BS Kim, CH Choi, GJ Cho, HO Jang and I Yun, Effects of Local Anesthetics on the Rate of Rotational Mobility of Phospholipid Liposomes, Journal of Biochemistry and Molecular Biology, 33(3):279-284, 2000 (SCIE)

3. KW Ahn, CH Choi, IS Kim, IK Chung, GJ Cho, HO Jang and I Yun, Transbilayer Effects of Chlorpromazine·HCl on Rotational Mobility of Synaptosomal Plasma Membrane Vesicles Isolated from Bovine Brain, Journal of Biochemistry and Molecular Biology, 33(6):541-547, 2000 (SCIE)

4. I Yun, ES Cho, HO Jang, UK Kim, CH Choi, IK Chyng, IS Kim and WG Wood, Amphiphilic Effect of Local Anesthetics on Rotational Mobility in Neuronal and Model Membranes, Biochimica et Biophysica Acta, 1564(1):123-132, 2002 (SCI)

5. HO Jang, HG Shin and I Yun, Effects of Dimyristoylphosphatidylethanol on the Structural Parameters of Neuronal Membranes, Molecules and Cells, 17(3):485-491, 2004 (SCI)

6. MK Bae, MH Huh, SW Lee, HG Kang, MH Kwak, HO Jang and I Yun, Effects of Dopamine·HCI on Structural Parameters of Bovine Brain Membranes, Archives of Pharmacal Research, 27(6):653-661, 2004 (SCIE)

7. HO Jang, DK Jeong, SH Ahn, CD Yoon, SC Jeong, SD Jin and I Yun, Effects of Chlorpromazine·HCI on the Structural Parameters of Bovine Brain Membranes, Journal of Biochemistry and Molecular Biology, 37(5):603-611, 2004 (SCIE)

8. MK Bae, DK Jeong, NS Park, CH Lee, BH Cho, HO Jang and I Yun, The Effect of Ethanol on the Physical Properties of Neuronal Membranes, Molecules and Cells, 19(3):356-364, 2005 (SCI)

9. HO Jang, MH Huh, SW Lee, YH Lee, JH Lee, JB Seo, KI Koo, SD Jin, JH Jeong, JS Lim, MK Bae and I Yun, The Effect of Dimyristoyplphosphatidylethanol on the Lateral and Rotational Mobilities of Liposome Lipid Bilayers, Archives of Pharmacal Research, 28(7):839-847, 2005 (SCIE)

10. SK Bae, SR Kim, JG Kim, JY Kim, TH Koo, HO Jang, I Yun, MA Yoo and MK Bae, Hypoxic Induction of Human Visfatin Gene is Directly Mediated by Hypoxia-Inducible Factor-1, FEBS letters, 580(17):4105-4113, 2006 (SCI)

11. TH Koo, HO Jun, SK Bae, SR Kim, CP Moon, SK Jeong, WS Kim, GC Kim, HO Jang, I Yun, KW Kim and MK Bae, Porphyromonas gingivalis, Periodonatal Pathogen, Lipopolysaccharide Induces Angiogenesis via Extracellular Signal-Regulated Kinase1/2 Activation in Human Vascular Endothelial Cells, Archives of Pharmacal Research, 30(1):34-42, 2007 (SCIE)

12. YH Lee, NS Park, JD Kwon, JS Park, GB Shin, CS Lee, TS Jung, NJ Choi, JH Yoon, JS Ok, UC Yoon, MK Bae, HO Jang and I Yun, Amphiphilic Effect of Dibucaine·HCl on Rotational Mobility of n-(9-Anthroyloxy)stearic acid in Neuronal and Model Membranes, Chemistry and Physics of Lipids, 146:33-42, 2007 (SCI)

13. SR Kim, SK Bae, KS Choi, SY Park, HO Jun, JY Lee, HO Jang, I Yun, KH Yoon, YJ Kim, MA Yoo, KW Kim and MK Bae, Visfatin Promotes Angiogenesis by Activation of Extracellular Signal-Regulated Kinase 1/2, Biochemical and Biophysical Research Communications, 357:150-156, 2007 (SCI)

14. HO Jang, YS Park, JH Lee, JB Seo, KI Koo, SC Jeong, SD Jin, YH Lee, HS Eom and I Yun, Effect of Extracts from Safflower Seeds on Osteoblast Differentiation and Intracellular Calicium Ion Concentration in MC3T3-E1 Cells, Natural Product Research, 21(9):287-297, 2007 (SCIE)

15. HO Jang, JS Kim, WC Kwon, JK Kim, MS Ko, DH Kim, WI Kim, YC Jeon, IK Chung, SH Shin, J Chung, MK Bae and I Yun, The Effects of Lead on Calcium Release Activated Calcium Influx in Primary Cultures of Human Osteoblast-like Cells, Archives of Pharmacal Research, 31(2):188-194, 2008 (SCIE)

16. SR Kim, YH Bae, SK Bae, KS Choi, KH Yoon, TH Koo, HO Jang, I Yun, KW Kim, YG Kwon, MA Yoo and MK Bae, Visfatin Enhances ICAM-1 and VCAM-1 Expression through ROS-Dependent NF-KappaB Activation in Endothelial Cells, Biochimica et Biophysica Acta, 1783(5):886-895, 2008 (SCI)

17. JH Lee, DI Kim, H Mun, SK Lee, JS Park, JH Kim, JH Lee, YH Park, YC Jeon, UC Yoon, MK Bae, HO Jang, WG Wood and I Yun, The Effect of Propoxycaine?HCl on the Physical Properties of Neuronal Membranes, Chemistry and Physics of Lipids, 154:19-25, 2008 (SCI)

 

Academic avtivities

1. member of Dong-Euipathology society

2. member of Korean Pharmacology Association 

3. member of Korean Pharmacy Society

4. member of Korea Optical science society

5. member of Korea cell molecular biology society

6. director of Pusan National University Oral Biotechnology Institute